Modified reperfusion and ischemia-reperfusion injury in human lung transplantation
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چکیده
منابع مشابه
Is adalimumab protective in ischemia-reperfusion injury in lung?
Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I-R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor-alpha (TNF-α) inhibitor agent. We aimed to evaluate whether Ada would prevent the lung tissue from damage development over the I-R process. Materials and Methods:Twenty seven Wistar albino male rats were divided into...
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............................................................................................................. 6 Original publications ...................................................................................... 7 Abbreviations .................................................................................................... 8 Introduction ...............................................
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Ischemia and reperfusion have been a natural step during kidney transplantation. Impairment of blood flow starts with brain death due to severe hemodynamic disturbances in cadaveric donor. Clamping of renal artery causes an absolute ischemia during harvesting operation. Cold ischemia during allograft kidney storage may also cause additional ischemic damages (Southard et al. 1985; Ploeg et al.19...
متن کاملIschemia-reperfusion injury in kidney transplantation.
Ischemia-reperfusion injury to the kidney is a complex pathophysiological process that has importance during transplantation as it affects graft function and survival. It starts with the physiological changes associated with the death of the donor, including the direct effects of hypoxia and metabolic stress. The injury continues through the organ procurement and preservation procedures. Upon r...
متن کاملEffect of renal ischemia-reperfusion on lung injury and inflammatory responses in male rat
Objective(s):Acute kidney injury (AKI), a syndrome characterized by decreased glomerular filtration, occurs in every 1 of 5 hospitalized patients. Renal ischemia-reperfusion, one of the main causes of AKI, is of particular importance in the setting of kidney transplantation. Materials and Methods: Sixty male rats were divided into four groups including control, nephrectomy, sham surgery and re...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2003
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(03)00976-0